Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

2. FRANCE: Pro-Migrant Activist Reportedly Murdered by Afghan Migrant He Housed

President of pro-migrant association killed, young Afghan migrant in custody

The president of a pro-migrant association that delivered assistance to the homeless was found murdered at his home in Bretteville-en-Saire, east of Cherbourg-en-Cotentin (Manche), according to Actu.

Retired teacher and former director of Gonneville School, Jean Dussine, 63, was president of Itinérance, a group that helped vulnerable migrants.

 

Dussine was found dead this morning at his home, believed to be beaten with an iron rod as he slept.

Migrants, who Dussine was hosting, sounded the alarm when they found the educator’s dead body, according to Ouest France.

 

Since the brutal murder, a young twenty-year-old Afghan migrant, who Dussine had been housing, has been arrested and placed under local police custody.

It has been reported that the migrant in custody cannot speak French.

 

Detectives and criminologists are reportedly at the scene of the crime, processing the former teacher’s home for evidence.

 

According to Valeurs Actuelles, it was reported that Dussine “was sleeping when [the alleged assailant], an Afghan migrant barely 20 years old, attacked him with an iron rod. He could not be revived.”

(Last year, a migrant stabbed to death a 27 year old med student ex-lover)

3. Egypt: ISIS beheads three youths in Sinai, sources

(ANSAmed) – CAIRO, MAY 12 – ISIS terrorists ”have beheaded three youths and kidnapped three others from the tribe of the Terabin, one of Sinai’s largest” local sources said Tuesday.

The heads of the three victims ”were found on the main road”, the sources added, without providing further details but attributing the crime to the so-called Islamic State ‘Daesh’ terror group.

A low-intensity conflict has been ongoing over the past six years, mainly in the north-east of the Egyptian peninsula,a between security forces and the Egyptian branch of ISIS with a high number of victims from both sides. Local tribes are also targeted by terrorists when they cooperate with security forces, providing information. In 2015, ten men were beheaded and their murder was filmed. Earlier this month, 18 terrorists were killed in an operation carried out by Egyptian security forces in northern Sinai.

4. Shopping fashion

5. Gen Ident action to stop call to prayer in Århus

(Practicing bagpipes across the road from the minaret would also be effective. But anyone actually doing anything at all to stop this is refreshing)

6. Hydroxychloroquine–Number Of Prescriptions Explodes In France

(Notice first sentence for propaganda value)

Despite the warnings around taking hydroxychloroquine to combat the symptoms of COVID-19, prescriptions in France have increased by as much as 7,000% in certain parts of the country since the pandemic began.

 

As reported by La Provence, a study looking at the 466 million French prescriptions written since the pandemic began in France, show a huge spike in doctors prescribing the drug. In the last week of March, for instance, over 10,000 people were prescribed hydroxychloroquine in Marseille alone. In France and the U.S., the use of hydroxychloroquine has been fraught between those who think the risks are small enough to warrant widespread use and those who think that more research is required before widespread prescription.

 

Following research conducted in China, a French doctor, Didier Raoult–head of the IHU, the Institute of Infectious Diseases in Marseille–claimed at the beginning of March that he had successfully treated patients suffering from coronavirus with the drug. Hydroxychloroquine is an anti-malarial drug also used to treat people suffering from lupus. It is sold under its trader name of Plaquénil in France.

(Question: Hydroxychloroquine is either a dangerous drug that is as likely to kill you or help you, or taking it is a problem because so many people with other diseases need it and getting it will shorten the supply of this extremely common medicine which costs ten cents a pill and has been around for a hundred years. Which is it. Because it cannot be both.)

7. Ted Cruz committing the crime of getting a haircut

8. PREVIOUSLY TARGETED KOSHER RESTAURANT HIT IN SUSPECTED ARSON ATTEMPT

Kosher restaurant Ha Carmel on Amstelveenseweg in Amsterdam was vandalized on Friday morning. One of its windows was broken. The police arrested a suspect, using pepper spray during the arrest, the Amsterdam police said on Twitter. This not the first time Ha Carmel was targeted in recent years.

 

According to interest group Federatief Joods Nederland, the perpetrator wanted to set fire to the restaurant. The organization posted a photo of the damage on Twitter.

The police are investigating the vandalism and the motive behind it.

(Mass muslim importation is genocide of the Jewish peoples by proxy. Most certainly by the UN definition of the term. However by that definition, the UN is doing genocide of Europeans itself by the same process.)

9. Massive Protest Breaks Out in India’s Kashmir as Security Personnel Shoot Civilian Dead – Video

(Kashmir unrest has not stopped during this health measures act)

10. ‘Giant Screwup’: FBI Mistakenly Leaks Name of Saudi Official Suspected of Involvement in 9/11