Discrimination against Jews and Muslims is on the rise around the world, according to an annual US Department of State report.
The findings for 2012 spoke of an increase in anti-Islamic sentiment in Europe and Asia.
It also said there was growing anti-Semitism, especially in Venezuela, Egypt and Iran.
As he unveiled the report, US Secretary of State John Kerry appointed a new special envoy on anti-Semitism.
Ira Foreman was named to replace Michael Kozak in the role, which was first created in 2004.
Mr Foreman was in charge of appealing to Jewish voters on behalf of President Barack Obama ahead of last November’s election.
The International Religious Freedom Report, released on Monday, noted that in Egypt, anti-Semitic sentiment in the media sometimes included Holocaust denial or glorification.
It also mentioned an incident on 19 October when Egyptian President Mohammed Morsi said “amen” to a religious leader’s call upon Allah to “destroy the Jews and their supporters”.